Opportunity Information: Apply for PA 18 586

The Research Supplements to Promote Diversity in Health-Related Research (Administrative Supplement - Clinical Trial Not Allowed), Funding Opportunity Number PA-18-586, is a discretionary grant mechanism offered by the National Institutes of Health (NIH) in partnership with the Centers for Disease Control and Prevention (CDC). Rather than funding brand-new, stand-alone projects, this opportunity provides administrative supplement funds to existing NIH/CDC-supported research grants (limited to specific eligible activity codes referenced in the full announcement). The central purpose is to strengthen and diversify the biomedical, behavioral, clinical, and social sciences research workforce by enabling current grant-holding projects to bring in and support additional trainees or investigators who contribute to workforce diversity.

A key feature of this program is that it is designed to recruit and support individuals from groups that have been demonstrated to be underrepresented in health-related research. In practical terms, the supplement funds are typically used to add a supported role on an active grant for a student, postdoctoral researcher, or eligible investigator whose participation both advances their research development and helps address longstanding representation gaps across the health research enterprise. The supplement is meant to create a structured, mentored research experience tied directly to the science already funded under the parent award, with the expectation that the supported individual gains meaningful research skills, publications or presentations where appropriate, and stronger preparation for the next stage of their career.

The announcement also explicitly states a second, related purpose: it can provide added support for a Program Director/Principal Investigator (PD/PI) on an existing research grant who is or becomes disabled and needs reasonable accommodations or additional resources to continue contributing effectively to the project. In this use case, the supplement is meant to remove barriers to participation and productivity so that the PD/PI can maintain research momentum and meet the aims of the funded project without needing to restructure the award into a separate effort.

Because these are administrative supplements, the supported activities must remain within the scope of the original, already-approved project. That generally means the supplement cannot be used to launch a substantially new research direction, build an unrelated training program, or expand into aims that would require a major scientific re-review. The supplement should clearly map onto the parent grant's goals and methods, showing how the added person or added support will contribute to ongoing experiments, analyses, or other project tasks that the grant was designed to accomplish. The title also signals an important restriction: clinical trials are not allowed under this specific supplement opportunity, so the proposed supplement activities should not introduce a clinical trial component if one is not already permitted, and they should align with the "clinical trial not allowed" framework described in NIH policy.

Eligibility is anchored to organizations that already hold qualifying research grants and are applying to add a diversity-focused supplement or disability accommodation supplement to that active award. The listing provided identifies eligible applicants as public and state-controlled institutions of higher education, reflecting a common base of academic and public research institutions that manage NIH awards. The announcement also clarifies important limits on foreign involvement: non-domestic (non-U.S.) entities, meaning foreign institutions, are not eligible to apply as applicants, and non-domestic components of U.S. organizations are also not eligible to apply. At the same time, foreign components, as defined in the NIH Grants Policy Statement, are allowed, meaning certain project elements can be conducted internationally when permitted under NIH rules and when justified scientifically, even though the applicant organization itself must be eligible and domestic.

From an administrative standpoint, this opportunity is cataloged across many CFDA numbers (reflecting that supplements can attach to awards funded under numerous NIH institutes and centers and program areas). The opportunity was created on January 24, 2018, with an original closing date listed as August 22, 2018, indicating the specific window associated with the posting details you provided. The notice does not specify an award ceiling or expected number of awards in the excerpt, which is typical for supplement programs because budgets and award counts depend heavily on institute priorities, availability of funds, and the number and quality of supplement requests tied to active parent grants.

Overall, PA-18-586 is best understood as a targeted add-on funding option for current NIH/CDC grantees to (1) bring underrepresented individuals into meaningful, mentored research roles on active projects and/or (2) ensure that a disabled PD/PI can continue performing their role on the funded research through needed support. The emphasis is on practical workforce impact, direct integration into the parent project, and adherence to the original scientific scope, with explicit restrictions around applicant geography and the prohibition on clinical trials under this supplement pathway.

  • The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.310, 93.313, 93.350, 93.351, 93.361, 93.393, 93.394, 93.395, 93.396, 93.398, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.859, 93.865, 93.866, 93.867, 93.879, 93.989.
  • This funding opportunity was created on 2018-01-24.
  • Applicants must submit their applications by 2018-08-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education.
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Frequently Asked Questions (FAQs)

What is the PA-18-586 opportunity?

PA-18-586, titled Research Supplements to Promote Diversity in Health-Related Research (Administrative Supplement - Clinical Trial Not Allowed), is an administrative supplement funding opportunity offered by the National Institutes of Health (NIH) in partnership with the Centers for Disease Control and Prevention (CDC). It is intended to add funds to an existing NIH/CDC-supported research award rather than fund a brand-new, stand-alone project.

Is this funding for new, independent research projects?

No. This program provides administrative supplements to support activities that remain within the scope of an already-funded parent grant. It is not designed to launch a separate research project.

What is the main purpose of this supplement?

The central purpose is to strengthen and diversify the health-related research workforce by enabling active NIH/CDC-funded projects to recruit and support additional trainees or investigators who contribute to diversity in biomedical, behavioral, clinical, and social sciences research fields.

Who is this supplement meant to support?

It is designed to recruit and support individuals from groups that have been demonstrated to be underrepresented in health-related research. In practical terms, supplement funds are typically used to add a supported role on an active grant for a student, postdoctoral researcher, or eligible investigator whose participation advances their research development while addressing representation gaps.

Does the opportunity also support accommodations for disability?

Yes. The announcement states a second purpose: it can provide added support for a Program Director/Principal Investigator (PD/PI) on an existing research grant who is or becomes disabled and needs reasonable accommodations or additional resources to continue contributing effectively to the project.

How must the proposed supplement activities relate to the parent award?

Because these are administrative supplements, the supported activities must stay within the scientific scope of the original, already-approved project. The request should clearly map to the parent grant's goals and methods and explain how the added person or added support will contribute to ongoing work the grant was designed to accomplish.

Can the supplement be used to start a substantially new research direction or unrelated training program?

No. The supplement generally cannot be used to launch a substantially new research direction, build an unrelated training program, or expand into aims that would require a major scientific re-review. The intent is to augment and support the existing approved project.

Are clinical trials allowed under this supplement opportunity?

No. The title and description explicitly state that this is an administrative supplement where clinical trials are not allowed. Proposed supplement activities should not introduce a clinical trial component and should align with the NIH "clinical trial not allowed" framework.

Who can apply for PA-18-586?

Eligibility is anchored to organizations that already hold qualifying NIH/CDC-supported research grants and are applying to add a diversity-focused supplement or a disability accommodation supplement to that active award. The listing provided identifies eligible applicants as public and state-controlled institutions of higher education.

Do applicants need to already have an NIH/CDC award to request this supplement?

Yes. This opportunity is an add-on to an existing NIH/CDC-supported grant. The supplement request is tied directly to an active parent award and is limited to specific eligible activity codes referenced in the full announcement.

Are foreign institutions eligible to apply as the applicant organization?

No. The announcement states that non-domestic (non-U.S.) entities, meaning foreign institutions, are not eligible to apply as applicants. In addition, non-domestic components of U.S. organizations are also not eligible to apply.

Are foreign components allowed at all?

Yes. While the applicant organization must be eligible and domestic, the announcement indicates that foreign components (as defined in the NIH Grants Policy Statement) are allowed when permitted under NIH rules and justified scientifically.

What kinds of outcomes or benefits are expected for the supported individual under the diversity purpose?

The supplement is meant to create a structured, mentored research experience tied directly to the parent award. The expectation is that the supported individual gains meaningful research skills and, where appropriate, contributes to publications or presentations and strengthens preparation for the next stage of their career.

What is the role of the parent grant in determining what can be proposed?

The parent grant defines what is allowable. The supplement should support experiments, analyses, or other tasks that fit the parent award's approved aims and methods, rather than expanding beyond what the original project was designed to do.

Which agencies are associated with this funding opportunity?

This opportunity is offered by the National Institutes of Health (NIH) in partnership with the Centers for Disease Control and Prevention (CDC).

What is the Funding Opportunity Number for this program?

The Funding Opportunity Number is PA-18-586.

Is there an award ceiling or a stated number of awards in the provided information?

No. The excerpt does not specify an award ceiling or the expected number of awards. This is typical for supplement programs because budgets and award counts often depend on institute priorities, availability of funds, and the number and quality of supplement requests tied to active parent grants.

What CFDA numbers apply to this opportunity?

The opportunity is cataloged across many CFDA numbers, reflecting that supplements can attach to awards funded under multiple NIH institutes and centers and program areas. The provided excerpt does not list specific CFDA numbers.

When was PA-18-586 created and what closing date is listed in the provided details?

The opportunity was created on January 24, 2018, and the posting details provided list an original closing date of August 22, 2018.

In one sentence, what is the best way to understand PA-18-586?

PA-18-586 is a targeted administrative supplement option for current NIH/CDC grantees to add diversity-focused mentored research support and/or provide needed support for a disabled PD/PI, while staying within the parent award's scope and avoiding clinical trials.

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Applicants also applied for:

Applicants who have applied for this opportunity (PA 18 586) also looked into and applied for these:

Funding Opportunity
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp - Clinical Trial Optional) Apply for PA 18 591

Funding Number: PA 18 591
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 18 589

Funding Number: PA 18 589
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Change of Grantee Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 18 590

Funding Number: PA 18 590
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed ) Apply for PA 18 592

Funding Number: PA 18 592
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 18 648

Funding Number: PA 18 648
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) Apply for PA 18 658

Funding Number: PA 18 658
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31) Apply for PA 18 666

Funding Number: PA 18 666
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 668

Funding Number: PA 18 668
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 18 671

Funding Number: PA 18 671
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 18 670

Funding Number: PA 18 670
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Ruth L. Kirschstein National Research Service Award (NRSA)Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 673

Funding Number: PA 18 673
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 18 740

Funding Number: PAR 18 740
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Administrative Supplements for Research on Dietary Supplements (Admin. Supp.- Clinical Trial Not Allowed) Apply for PA 18 817

Funding Number: PA 18 817
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: $100,000
Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 19 056

Funding Number: PA 19 056
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 19 116

Funding Number: PA 19 116
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) Apply for PA 19 117

Funding Number: PA 19 117
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Mentored Quantitative Research Development Award (Parent K25 - Independent Clinical Trial Required) Apply for PA 19 125

Funding Number: PA 19 125
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed) Apply for PA 19 119

Funding Number: PA 19 119
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required) Apply for PA 19 118

Funding Number: PA 19 118
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent
Administrative Supplement for Research on Sex/Gender Influences (Admin Supp Clinical Trial Optional) Apply for PA 19 165

Funding Number: PA 19 165
Agency: National Institutes of Health
Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services
Funding Amount: Case Dependent

 

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