Opportunity Information: Apply for RFA CA 16 017
The Coordinating Center for Population-based Research to Optimize Cancer Screening (PROSPR) (U24) opportunity (Funding Opportunity Number RFA-CA-16-017) is a National Cancer Institute (NCI) cooperative agreement intended to support the central coordinating infrastructure for the PROSPR program. PROSPR is an NCI initiative focused on population-based research that examines how cancer screening works in real-world practice and how the entire screening process can be improved. Rather than looking only at whether a test can detect cancer under ideal conditions, the PROSPR program emphasizes understanding what happens across the full screening pathway as it is delivered in routine health care settings, including how screening is implemented, how follow-up occurs, and what effects screening has across diverse populations and systems.
This U24 award is specifically for a single Coordinating Center that will serve as the hub for the larger PROSPR network. The companion announcement (RFA-CA-16-016) funds the PROSPR UM1 Research Centers, and the Coordinating Center is designed to connect and support those research sites. In practical terms, the Coordinating Center role typically includes network-wide coordination, harmonization of approaches across participating centers, facilitation of communication and collaboration, and support for shared activities that allow results from multiple health care environments to be compared or combined. Because this is a cooperative agreement, the project is expected to involve substantial scientific and programmatic involvement from NIH/NCI staff compared to a standard grant, with the intent of actively guiding and integrating work across the consortium.
The overall program goal tied to this opportunity is to enhance understanding of how cancer screening is implemented and what impacts it has when delivered in multiple health care environments across the United States. That emphasis on multiple environments signals interest in variability in screening delivery across different systems of care, patient populations, and operational contexts, and in generating evidence that can inform improvements to the screening process at the population level. The Coordinating Center is the mechanism NCI uses to make the network function as a coherent, comparable, and efficient research enterprise, so that insights about screening processes and outcomes can be synthesized across centers rather than remaining siloed.
Administratively, the award is offered by the Department of Health and Human Services through the National Institutes of Health, with NCI as the sponsoring institute. The opportunity is categorized as discretionary funding and uses the cooperative agreement funding instrument. The activity category is listed under education and health, and the CFDA numbers associated with the program are 93.393, 93.394, 93.395, and 93.399. The funding opportunity was created on October 24, 2016, and the original application closing date was February 9, 2017.
In terms of funding scale, the expected number of awards is one, reflecting the intention to establish a single Coordinating Center for the PROSPR network. The listed award ceiling is $1,000,000, which indicates the maximum anticipated annual or total award amount as specified in the announcement summary. Eligibility is broad and includes many types of domestic organizations and governments, such as state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other applicants as described in the full eligibility text of the FOA.
Taken together, this opportunity funds the organizational and scientific coordination backbone for a national research effort aimed at improving cancer screening as it is actually delivered in U.S. health care systems. The key idea is that better screening outcomes depend not only on the screening test itself, but also on how people are reached, screened, followed up, diagnosed, and managed across a sequence of steps that can break down in practice. The Coordinating Center is positioned to enable consistent methods and shared learning across the PROSPR Research Centers so that the program can produce more generalizable, system-relevant evidence about optimizing the screening process.Apply for RFA CA 16 017
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Coordinating Center for Population-based Research to Optimize Cancer Screening (PROSPR) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.399.
- This funding opportunity was created on Oct 24, 2016.
- Applicants must submit their applications by Feb 09, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the PROSPR Coordinating Center (U24) funding opportunity?
This opportunity is a National Cancer Institute (NCI) cooperative agreement (U24) to support a single Coordinating Center for the Coordinating Center for Population-based Research to Optimize Cancer Screening (PROSPR) program. The Funding Opportunity Number is RFA-CA-16-017.
What does PROSPR stand for, and what is the program about?
PROSPR stands for Population-based Research to Optimize Cancer Screening. It is an NCI initiative focused on population-based research that studies how cancer screening works in real-world practice and how the entire screening process can be improved across routine health care settings.
What is meant by studying cancer screening in "real-world practice"?
In the PROSPR context, "real-world practice" means examining screening as it is delivered in routine health care environments, not just whether a screening test can detect cancer under ideal conditions. This includes understanding how screening is implemented, how follow-up happens, and what effects screening has across different populations and health systems.
What is the "full screening pathway" referenced in the opportunity description?
The full screening pathway refers to the sequence of steps involved in screening as delivered in practice. The description emphasizes looking beyond the screening test itself to include how people are reached, screened, followed up, diagnosed, and managed, and where that process can break down in routine care.
What is the main purpose of the U24 Coordinating Center award?
The U24 award is intended to fund the central coordinating infrastructure that allows the PROSPR network to function as a coherent, comparable, and efficient research enterprise. The Coordinating Center serves as the hub that connects and supports the PROSPR Research Centers.
How does the Coordinating Center relate to the PROSPR Research Centers?
The Coordinating Center is designed to connect and support the PROSPR UM1 Research Centers funded under the companion announcement RFA-CA-16-016. The Coordinating Center enables network-wide coordination and shared activities so that findings can be compared or synthesized across multiple health care environments.
Is this funding opportunity intended to support multiple Coordinating Centers?
No. The expected number of awards is one, reflecting the intent to establish a single Coordinating Center for the PROSPR network.
What kinds of activities does the Coordinating Center typically support?
Based on the opportunity description, the Coordinating Center role typically includes network-wide coordination, harmonization of approaches across participating centers, facilitation of communication and collaboration, and support for shared activities that allow results from multiple health care environments to be compared or combined.
What is the overall program goal tied to this opportunity?
The goal is to enhance understanding of how cancer screening is implemented and what impacts it has when delivered in multiple health care environments across the United States, with attention to variability across systems of care, populations, and operational contexts.
Why does the opportunity emphasize "multiple health care environments"?
The emphasis signals an interest in understanding differences in how screening is delivered across diverse systems and contexts, and in generating evidence that can inform improvements to screening processes at the population level.
What does it mean that this award is a cooperative agreement?
A cooperative agreement indicates substantial scientific and programmatic involvement from NIH/NCI staff compared to a standard grant. The intent is active guidance and integration of work across the consortium rather than purely investigator-driven, independent projects.
Which federal agencies are offering and administering this opportunity?
The award is offered by the U.S. Department of Health and Human Services through the National Institutes of Health (NIH), with the National Cancer Institute (NCI) as the sponsoring institute.
How is the opportunity categorized in terms of funding type and activity area?
The opportunity is categorized as discretionary funding and uses the cooperative agreement funding instrument. The activity category is listed under education and health.
What CFDA numbers are associated with this program?
The CFDA numbers listed for this opportunity are 93.393, 93.394, 93.395, and 93.399.
What is the Funding Opportunity Number (FOA number) for this announcement?
The Funding Opportunity Number is RFA-CA-16-017.
When was this funding opportunity created, and when did applications close?
The funding opportunity was created on October 24, 2016, and the original application closing date was February 9, 2017.
How much funding is available under this opportunity?
The award ceiling listed in the announcement summary is $1,000,000, indicating the maximum anticipated annual or total award amount as specified in the summary.
How many awards does NCI expect to make under this FOA?
The expected number of awards is one.
Who is eligible to apply?
Eligibility is broad and includes many types of domestic organizations and governments, including state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; small businesses; and other applicants as described in the full eligibility text of the FOA.
Does this opportunity focus on improving the screening test itself?
The description emphasizes that better screening outcomes depend not only on the screening test, but also on how the screening process is delivered across the full pathway in practice. The program focus is on optimizing the screening process as implemented in real-world health care systems.
Why is a Coordinating Center important for this kind of research program?
Because the program spans multiple research sites and health care environments, the Coordinating Center is positioned to enable consistent methods, harmonized approaches, and shared learning across the PROSPR Research Centers. This helps ensure insights about screening processes and outcomes can be synthesized across centers rather than remaining siloed.
What is the companion announcement mentioned in the description?
The companion announcement is RFA-CA-16-016, which funds the PROSPR UM1 Research Centers. The U24 Coordinating Center funded under RFA-CA-16-017 is designed to connect and support those UM1 sites.
What is the key idea behind the PROSPR program as described here?
The central idea is that improving cancer screening outcomes requires understanding and improving not just the screening test, but also the real-world delivery process: reaching eligible people, conducting screening, ensuring follow-up, confirming diagnoses, and managing care across steps that can fail or vary across systems.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA CA 16 017) also looked into and applied for these:
| Funding Opportunity |
|---|
| Research Centers for Population-based Research to Optimize Cancer Screening (PROSPR) Initiative (UM1) Apply for RFA CA 16 016 Funding Number: RFA CA 16 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $2,500,000 |
| FY 2017 American Schools and Hospitals Abroad (ASHA) Program (Request for Comments) Apply for APS ASHA 17 000001 Funding Number: APS ASHA 17 000001 Agency: Agency for International Development Category: Education, Health Funding Amount: $2,000,000 |
| Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33) Apply for RFA CA 17 013 Funding Number: RFA CA 17 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Innovative Technologies for Cancer-Relevant Biospecimen Science (R21) Apply for RFA CA 17 012 Funding Number: RFA CA 17 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33) Apply for RFA CA 17 011 Funding Number: RFA CA 17 011 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| PDX Data Commons and Coordinating Center (PDCCC) for the PDX Development and Trial Centers Research Network (PDXNet) (U24) Apply for RFA CA 17 004 Funding Number: RFA CA 17 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $650,000 |
| PDX Development and Trial Centers (PDTCs) (U54) Apply for RFA CA 17 003 Funding Number: RFA CA 17 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $800,000 |
| Mechanisms of Cancer Drug Resistance and Sensitivity (U54) Apply for RFA CA 17 009 Funding Number: RFA CA 17 009 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
| Consortium for Pancreatic Ductal Adenocarcinoma (PDAC) Translational Studies on the Tumor Microenvironment (U01) Apply for RFA CA 17 015 Funding Number: RFA CA 17 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Resource Center for the Consortium for Pancreatic Ductal Adenocarcinoma (PDAC) Translational Studies (U24) Apply for RFA CA 17 016 Funding Number: RFA CA 17 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Coordinating Center for Canine Immunotherapy Trials and Correlative Studies (U24) Apply for RFA CA 17 002 Funding Number: RFA CA 17 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Canine Immunotherapy Trials and Correlative Studies (U01) Apply for RFA CA 17 001 Funding Number: RFA CA 17 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $350,000 |
| Administrative Supplements to Promote Research Collaborations on Fusion Oncoproteins as Drivers of Childhood Cancer (Admin Supp) Apply for PA 17 138 Funding Number: PA 17 138 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $135,000 |
| Data Management and Coordinating Center (DMCC) for the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Collaborative Research Centers (CRC) (U24) Apply for RFA NS 17 022 Funding Number: RFA NS 17 022 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
| NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3) Apply for RFA DA 18 003 Funding Number: RFA DA 18 003 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| Intensive Longitudinal Analysis of Health Behaviors: Leveraging New Technologies to Understand Health Behaviors (U01) Apply for RFA OD 17 004 Funding Number: RFA OD 17 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Intensive Longitudinal Analysis of Health Behaviors: Leveraging New Technologies to Understand Health Behaviors (U24) Apply for RFA OD 17 005 Funding Number: RFA OD 17 005 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $300,000 |
| Integration and Validation of Emerging Technologies to Accelerate Cancer Research (R33) Apply for RFA CA 17 023 Funding Number: RFA CA 17 023 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $325,000 |
| Limited Competition: Palliative Care Research Cooperative (PCRC) (U2C) Apply for RFA NR 17 001 Funding Number: RFA NR 17 001 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| SBIR Phase II Bridge Awards to Accelerate the Development of Cancer Therapeutics, Imaging Technologies, Interventional Devices, Diagnostics, and Prognostics toward Commercialization (R44) Apply for RFA CA 17 024 Funding Number: RFA CA 17 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
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