Opportunity Information: Apply for RFA CA 19 009
The U.S.-China Program for Biomedical Collaborative Research (R01, Clinical Trial Optional) is a National Institutes of Health (NIH) grant opportunity designed to strengthen joint biomedical research between investigators based in the United States and investigators based in China. The main goal is to spur meaningful, coordinated collaborations that can move ideas from basic science through translational work and, when appropriate, into clinical research. The scientific scope is broad but clearly defined around major public health priorities, including cancer, environmental health, heart disease, blood disorders, diseases of the eye and visual system, mental health, and neurological disorders. The mechanism is an R01, meaning it supports well-developed research projects, and it allows (but does not require) clinical trials.
A defining feature of this program is that it requires a true paired submission to two funders: the U.S. team submits to NIH, while the China-based team submits to the National Natural Science Foundation of China (NSFC). The applications must be identical in scientific content, reflecting a single integrated research plan carried out collaboratively. Each side must also include the counterpart application as an attachment: the U.S. application to NIH must attach the Chinese (NSFC) application, and the Chinese application to NSFC must attach the NIH application. This structure is meant to ensure the collaboration is genuine and that both agencies are reviewing the same proposed work rather than parallel but different projects.
Eligibility on the U.S. side is broad and includes many common applicant types such as state, county, city, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; federally recognized Native American tribal governments; tribal organizations (including those other than federally recognized governments); public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The program also highlights additional eligible applicant categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. In contrast, it places firm limits on foreign involvement within the NIH application: non-domestic (non-U.S.) entities are not eligible to apply to NIH under this announcement, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. Practically, that means the NIH-funded portion of the work needs to be carried out within allowable U.S. organizational structures, while the Chinese side is supported through NSFC under its separate announcement.
From an administrative standpoint, this is a discretionary grant opportunity (Funding Instrument: Grant) associated with NIH and listed under the funding opportunity number RFA-CA-19-009. It falls under Education, Environment, and Health activity categories and references multiple CFDA numbers (93.113, 93.242, 93.393, 93.394, 93.395, 93.396, 93.397, 93.399, 93.853, 93.867), reflecting participation across several NIH institutes and program areas. The source data provided shows an original closing date of 2019-02-21 and an award ceiling figure of 150,000, though applicants typically need to confirm current budget rules and any institute-specific limits in the full solicitation and related NIH guidance. Overall, the opportunity is built for research teams that can demonstrate a tightly coordinated U.S.-China partnership, a shared and consistent scientific plan, and compliance with the strict rules limiting foreign components within the NIH-supported project.Apply for RFA CA 19 009
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "U.S.-China Program for Biomedical Collaborative Research (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.393, 93.394, 93.395, 93.396, 93.397, 93.399, 93.853, 93.867.
- This funding opportunity was created on 2019-01-02.
- Applicants must submit their applications by 2019-02-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQ)
What is the U.S.-China Program for Biomedical Collaborative Research (R01, Clinical Trial Optional)?
This is an NIH grant opportunity intended to strengthen joint biomedical research collaborations between investigators based in the United States and investigators based in China. It uses the NIH R01 mechanism and is designed to support well-developed research projects that can span basic science, translational research, and (when appropriate) clinical research.
What is the main purpose of this program?
The purpose is to spur meaningful, coordinated U.S.-China collaborations with a single, integrated research plan. The program is structured to support partnerships that can move ideas from basic research through translational work and, if appropriate, into clinical research.
What type of NIH funding mechanism is used?
The mechanism is an R01. In general, an R01 supports a well-developed research project with a clearly defined scientific plan.
Are clinical trials required under this opportunity?
No. Clinical trials are optional. The opportunity allows clinical trials, but they are not required for all applications.
What scientific areas does this program support?
The scope is broad but defined around major public health priorities, including:
- Cancer
- Environmental health
- Heart disease
- Blood disorders
- Diseases of the eye and visual system
- Mental health
- Neurological disorders
Is this a single application to NIH, or does it require submissions to two agencies?
It requires a paired submission to two funders. The U.S. team submits to NIH, and the China-based team submits to the National Natural Science Foundation of China (NSFC). The structure is intended to ensure both agencies review the same collaborative project.
Do the NIH and NSFC applications need to be the same?
Yes. The applications must be identical in scientific content and reflect a single integrated research plan carried out collaboratively by the U.S. and China teams.
What does "paired submission" mean in practice?
Each side must submit to its respective agency (NIH for the U.S. team, NSFC for the China team), and the scientific content must match. The program is specifically designed to prevent parallel but different projects from being reviewed as if they were one collaboration.
Do applicants have to include the counterpart application in their submission?
Yes. Each side must attach the counterpart application as an attachment: the U.S. application to NIH must attach the Chinese (NSFC) application, and the Chinese application to NSFC must attach the NIH application.
Why does the program require identical scientific content and cross-attachments?
The stated intent is to ensure the collaboration is genuine and coordinated, and that both funding agencies are evaluating the same proposed research plan.
Who is eligible to apply on the U.S. side?
Eligibility on the U.S. side is broad and includes:
- State, county, city, and special district governments
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Independent school districts
- Federally recognized Native American tribal governments
- Tribal organizations (including those other than federally recognized governments)
- Public housing authorities/Indian housing authorities
- Nonprofits with and without 501(c)(3) status (other than institutions of higher education)
- For-profit organizations (other than small businesses)
- Small businesses
Are any specific institution types explicitly highlighted as eligible?
Yes. The opportunity highlights additional eligible applicant categories, including:
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-serving Institutions
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Faith-based or community-based organizations
- Regional organizations
- Eligible federal agencies
- U.S. territories or possessions
Can a non-U.S. (foreign) organization apply directly to NIH under this announcement?
No. Non-domestic (non-U.S.) entities are not eligible to apply to NIH under this announcement.
Can a U.S. organization include a non-U.S. component in its NIH application?
No. Non-domestic components of U.S. organizations are not eligible under this announcement.
Are foreign components allowed in the NIH-supported project?
No. Foreign components (as defined by NIH policy) are not allowed.
How does the program handle the China-based part of the collaboration if NIH cannot fund foreign components?
The program is structured so that the NIH-funded portion is carried out within allowable U.S. organizational structures, while the China-based portion is supported separately through NSFC under its own announcement.
What is the funding instrument type?
The funding instrument is a discretionary grant opportunity (Funding Instrument: Grant) associated with NIH.
What is the NIH funding opportunity number (FOA number)?
The funding opportunity number referenced is RFA-CA-19-009.
Which activity categories are associated with this opportunity?
The opportunity is associated with Education, Environment, and Health activity categories.
What CFDA numbers are associated with this program?
The information provided references multiple CFDA numbers, indicating participation across several NIH institutes and program areas. The listed CFDAs are:
- 93.113
- 93.242
- 93.393
- 93.394
- 93.395
- 93.396
- 93.397
- 93.399
- 93.853
- 93.867
What was the closing date shown in the provided information?
The source data provided shows an original closing date of 2019-02-21.
What award ceiling is mentioned?
The source data provided shows an award ceiling figure of 150,000.
Should applicants rely on the award ceiling figure shown in the source data?
Not without verification. The information provided notes that applicants typically need to confirm current budget rules and any institute-specific limits in the full solicitation and related NIH guidance.
What makes an application a good fit for this program?
Based on the description, a strong fit would be a research team that can demonstrate a tightly coordinated U.S.-China partnership, present a shared and consistent scientific plan across both submissions, and comply with the strict NIH rules that prohibit foreign components within the NIH-supported project.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA CA 19 009) also looked into and applied for these:
| Funding Opportunity |
|---|
| Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed) Apply for PAR 19 158 Funding Number: PAR 19 158 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (Clinical Trials Not Allowed R25) Apply for PAR 19 164 Funding Number: PAR 19 164 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) Apply for PA 19 187 Funding Number: PA 19 187 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Summer Research Education Experience Program (R25 Clinical Trial Not Allowed) Apply for PAR 19 197 Funding Number: PAR 19 197 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $100,000 |
| Building Interdisciplinary Research Careers in Women's Health (BIRCWH); K12 Clinical Trial Optional Apply for RFA OD 19 020 Funding Number: RFA OD 19 020 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $600,000 |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R21 Clinical Trial Optional) Apply for PAR 19 252 Funding Number: PAR 19 252 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Influences on Aging: Effects of Extreme Weather and Disaster Events on Aging Populations (R01 Clinical Trial Optional) Apply for PAR 19 250 Funding Number: PAR 19 250 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Basic and Translational Research on Adducts in Cancer Risk Identification and Prevention (R01 Clinical Trial Optional) Apply for PAR 19 251 Funding Number: PAR 19 251 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 19 275 Funding Number: PAR 19 275 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Mechanism for Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trial Not Allowed) Apply for RFA ES 19 011 Funding Number: RFA ES 19 011 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Apply for RFA OD 19 029 Funding Number: RFA OD 19 029 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) Apply for PA 20 047 Funding Number: PA 20 047 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) Apply for PA 20 025 Funding Number: PA 20 025 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Data Repository (U24 - Clinical Trials Not Allowed) Apply for PAR 20 089 Funding Number: PAR 20 089 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Biomedical Knowledgebase (U24 - Clinical Trials Not Allowed) Apply for PAR 20 097 Funding Number: PAR 20 097 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R01 Clinical Trials Not Allowed) Apply for PAR 20 165 Funding Number: PAR 20 165 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (R21 Clinical Trials Not Allowed) Apply for PAR 20 168 Funding Number: PAR 20 168 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed) Apply for PA 20 174 Funding Number: PA 20 174 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trial Required) Apply for PA 20 171 Funding Number: PA 20 171 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 173 Funding Number: PA 20 173 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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