Opportunity Information: Apply for RFA CA 20 013
Revision Applications to Support the Application of Informatics Technology for Cancer Research (U24 Clinical Trial Optional), RFA-CA-20-013, is a National Cancer Institute (NCI) funding opportunity designed specifically for projects that already hold an active NCI U24 cooperative agreement for resource-related research. The goal is not to start a brand-new standalone effort, but to fund a revision (formerly called a competing revision) that meaningfully extends or accelerates the parent U24 project by incorporating cancer informatics technologies created through the NCI Informatics Technology for Cancer Research (ITCR) Program. In practical terms, the FOA is trying to speed the path from informatics tool development to real-world use in cancer research communities by encouraging teams who run established U24 resources to adopt, adapt, and integrate proven ITCR-supported methods, tools, or platforms into their ongoing work.
The core purpose is to stimulate novel collaborations and interdisciplinary integration. Many ITCR outputs are advanced software tools, data standards, analytic methods, and infrastructure components that can be highly impactful but require real deployment contexts, domain-specific tailoring, user support, and integration with existing research workflows to achieve broad uptake. This FOA is meant to incentivize exactly that step: taking informatics technology that has already been developed with ITCR support (current or prior) and embedding it into an active U24 resource project in a way that expands the original scientific questions, enables additional capabilities, or accelerates progress for the parent study. The larger programmatic intent is to enhance cancer research productivity and speed discovery by improving how researchers collect, manage, harmonize, analyze, and share data.
The mechanism is a cooperative agreement (U24), which generally means NCI expects substantial scientific and/or programmatic involvement during the project period, beyond what is typical for a standard grant. The FOA is labeled “Clinical Trial Optional,” indicating that proposed activities may include a clinical trial if appropriate, but a clinical trial is not required. The funding instrument falls under the broad activity category of education and health, and it is associated with CFDA number 93.396. The sponsoring agency is the U.S. Department of Health and Human Services, National Institutes of Health (NIH), specifically NCI.
Funding is relatively modest and targeted to the revision scope: the listed award ceiling is $100,000, and NCI anticipated making about four awards under this announcement. This structure signals that the revisions are expected to be focused, high-leverage add-ons that enable integration or deployment of ITCR technologies rather than large expansions of the parent program. The FOA was created on January 23, 2020, and the original closing date was November 18, 2020.
Eligibility is broad in a general sense (including various government entities, higher education institutions, nonprofits, for-profits, and small businesses), but the key practical constraint is embedded in the purpose statement: applications are meant to be revision requests from “currently funded NCI U24 resource-related research projects.” In other words, the applicant organization must already be the recipient of a qualifying NCI U24 award and must be proposing a revision to that active parent award. The revision must clearly build on the existing aims or accelerate the parent project by bringing in informatics methods, tools, or resources that were developed with ITCR program support, and it should be framed in terms of adoption, adaptation, integration, and community benefit rather than purely exploratory development.
Overall, this FOA is best understood as a bridge between informatics innovation and operational cancer research infrastructure. It aims to move ITCR-funded technologies into the hands of researchers and resource programs that can validate them at scale, improve them through real-world use, and embed them into widely used platforms or services, thereby expanding the reach and impact of NCI’s informatics investments.Apply for RFA CA 20 013
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Revision Applications to Support the Application of Informatics Technology for Cancer Research (U24 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.396.
- This funding opportunity was created on Jan 23, 2020.
- Applicants must submit their applications by Nov 18, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $100,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Applicants who have applied for this opportunity (RFA CA 20 013) also looked into and applied for these:
| Funding Opportunity |
|---|
| FY 2018 American Schools and Hospitals Abroad (ASHA) Program Apply for 72ASHA18RFA00001 Funding Number: 72ASHA18RFA00001 Agency: Agency for International Development Category: Education, Health Funding Amount: $2,000,000 |
| Utilizing Cohort Studies to Address Health Outcomes in Cancer Survivors (UG3/UH3 Clinical Trial Not Allowed) Apply for RFA CA 20 030 Funding Number: RFA CA 20 030 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
| Strengthening Institutional Capacity to Conduct Global Cancer Research in Low- and Middle-Income Countries (D43 Clinical Trial Not Allowed) Apply for RFA CA 20 031 Funding Number: RFA CA 20 031 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| Metastasis Research Network (U54 Clinical Trial Not Allowed) Apply for RFA CA 20 029 Funding Number: RFA CA 20 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,200,000 |
| Improving Smoking Cessation Interventions among People Living with HIV (R01 Clinical Trial Optional) Apply for RFA CA 20 035 Funding Number: RFA CA 20 035 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Improving Smoking Cessation Interventions among People Living with HIV (R21 Clinical Trial Optional) Apply for RFA CA 20 036 Funding Number: RFA CA 20 036 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Emergency Awards: Exosome-based Non-traditional Technologies Towards Multi-Parametric and Integrated Approaches for SARS-CoV-2 (U18 Clinical Trial Not Allowed) Apply for RFA OD 20 018 Funding Number: RFA OD 20 018 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) Apply for PAR 21 046 Funding Number: PAR 21 046 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) Apply for RFA CA 21 015 Funding Number: RFA CA 21 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $600,000 |
| Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) Apply for RFA CA 21 016 Funding Number: RFA CA 21 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Revision Applications to Support the Application of Informatics Technology for Cancer Research (U01 Clinical Trials Optional) Apply for RFA CA 21 018 Funding Number: RFA CA 21 018 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21 Clinical Trial Optional) Apply for RFA CA 21 013 Funding Number: RFA CA 21 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Revision Applications to Support the Application of Informatics Technology for Cancer Research (R01 Clinical Trials Optional) Apply for RFA CA 21 017 Funding Number: RFA CA 21 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| Revision Applications to Support the Application of Informatics Technology for Cancer Research (U24 Clinical Trial Optional) Apply for RFA CA 21 019 Funding Number: RFA CA 21 019 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $100,000 |
| NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3 Clinical Trial Optional) Apply for PAR 21 092 Funding Number: PAR 21 092 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Coordination and Dissemination Center (R24 Clinical Trial Optional) Apply for RFA DA 21 029 Funding Number: RFA DA 21 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $575,000 |
| Limited Competition to Convert the CNS HIV Antiretroviral Therapy Effects Research (CHARTER) Study Cohort to a Research Resource (R24 - Clinical Trial Not Allowed) Apply for RFA MH 21 170 Funding Number: RFA MH 21 170 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,250,000 |
| Proteogenomic Data Analysis Centers (PGDACs) for Clinical Proteomic Tumor Analysis Consortium (U24 Clinical Trial Not Allowed) Apply for RFA CA 21 024 Funding Number: RFA CA 21 024 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $550,000 |
| Proteogenomic Translational Research Centers (PTRCs) for Clinical Proteomic Tumor Analysis Consortium (U01 Clinical Trial Not Allowed) Apply for RFA CA 21 025 Funding Number: RFA CA 21 025 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
| Proteome Characterization Centers (PCCs) for Clinical Proteomic Tumor Analysis Consortium (U24 Clinical Trial Not Allowed) Apply for RFA CA 21 023 Funding Number: RFA CA 21 023 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $750,000 |
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