Opportunity Information: Apply for PAR 20 107

The National Institutes of Health (NIH) funding opportunity PAR-20-107, titled "Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)," supports the creation or strengthening of Developmental Centers for AIDS Research (D-CFARs). The main goal is to expand and improve HIV/AIDS research capacity by providing centralized administrative leadership and shared research infrastructure that individual labs and projects often cannot sustain on their own. Rather than funding a single research project, this P30 center grant mechanism is designed to build a supportive environment for many investigators by offering shared core facilities, specialized expertise, and coordinated services that make HIV/AIDS research more efficient, collaborative, and competitive.

A key emphasis of the D-CFAR program is interdisciplinary collaboration across the full spectrum of HIV/AIDS research. In practice, this means encouraging connections among basic science, clinical research (within the "clinical trial not allowed" limitation), behavioral and social sciences, epidemiology, implementation science, and other related disciplines that contribute to HIV prevention, treatment, cure research, comorbidities, and health equity. The D-CFAR structure is meant to reduce duplication of expensive resources, standardize methods where helpful, and accelerate research progress by giving investigators streamlined access to tools and support services that would otherwise be difficult to obtain through traditional stand-alone grants.

Another central purpose of the D-CFAR is developmental: it is explicitly intended to help institutions and research communities mature into a future, full-scale Centers for AIDS Research (CFAR). D-CFAR funding supports planning, coordination, and shared resources that can strengthen an institution's research base, foster new collaborations, and position investigators to compete successfully for a standard CFAR award later. In that sense, the program functions both as capacity-building and as a pathway toward a more comprehensive, sustained HIV/AIDS research center.

The FOA uses the grant funding instrument and falls within a broad health and social services activity category. It is associated with multiple CFDA numbers (including 93.121, 93.233, 93.242, 93.279, 93.307, 93.361, 93.393-93.396, 93.399, 93.837-93.840, 93.847, 93.855, 93.865-93.866, and 93.989), reflecting the multi-institute, cross-cutting nature of HIV/AIDS research support at NIH. The opportunity is listed as discretionary funding, with NIH as the sponsoring agency. The original closing date shown in the source information is July 28, 2022, and the award ceiling and expected number of awards are not specified in the provided text.

Eligibility is broad and includes many types of U.S.-based organizations and governments. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The FOA also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. This wide eligibility is consistent with the program's goal of expanding HIV research capacity and strengthening research networks in diverse settings.

At the same time, the FOA sets clear limits on non-U.S. applicants. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed. In practical terms, this means a U.S. applicant organization can include certain international collaborations or activities as a foreign component when permitted under NIH policy, but a foreign institution cannot serve as the primary applicant organization for this center grant.

Finally, the "Clinical Trial Not Allowed" designation means applicants must propose center activities and supported research that do not include NIH-defined clinical trials under this award. The D-CFAR is therefore positioned primarily as an infrastructure and capacity-building mechanism to support and coordinate HIV/AIDS research and investigator development, while staying within NIH rules that exclude clinical trial conduct under this particular FOA.

  • The National Institutes of Health in the education, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.233, 93.242, 93.279, 93.307, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.847, 93.855, 93.865, 93.866, 93.989.
  • This funding opportunity was created on 2020-02-03.
  • Applicants must submit their applications by 2022-07-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 20 107

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