Opportunity Information: Apply for PAR 20 107
The National Institutes of Health (NIH) funding opportunity PAR-20-107, titled "Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)," supports the creation or strengthening of Developmental Centers for AIDS Research (D-CFARs). The main goal is to expand and improve HIV/AIDS research capacity by providing centralized administrative leadership and shared research infrastructure that individual labs and projects often cannot sustain on their own. Rather than funding a single research project, this P30 center grant mechanism is designed to build a supportive environment for many investigators by offering shared core facilities, specialized expertise, and coordinated services that make HIV/AIDS research more efficient, collaborative, and competitive.
A key emphasis of the D-CFAR program is interdisciplinary collaboration across the full spectrum of HIV/AIDS research. In practice, this means encouraging connections among basic science, clinical research (within the "clinical trial not allowed" limitation), behavioral and social sciences, epidemiology, implementation science, and other related disciplines that contribute to HIV prevention, treatment, cure research, comorbidities, and health equity. The D-CFAR structure is meant to reduce duplication of expensive resources, standardize methods where helpful, and accelerate research progress by giving investigators streamlined access to tools and support services that would otherwise be difficult to obtain through traditional stand-alone grants.
Another central purpose of the D-CFAR is developmental: it is explicitly intended to help institutions and research communities mature into a future, full-scale Centers for AIDS Research (CFAR). D-CFAR funding supports planning, coordination, and shared resources that can strengthen an institution's research base, foster new collaborations, and position investigators to compete successfully for a standard CFAR award later. In that sense, the program functions both as capacity-building and as a pathway toward a more comprehensive, sustained HIV/AIDS research center.
The FOA uses the grant funding instrument and falls within a broad health and social services activity category. It is associated with multiple CFDA numbers (including 93.121, 93.233, 93.242, 93.279, 93.307, 93.361, 93.393-93.396, 93.399, 93.837-93.840, 93.847, 93.855, 93.865-93.866, and 93.989), reflecting the multi-institute, cross-cutting nature of HIV/AIDS research support at NIH. The opportunity is listed as discretionary funding, with NIH as the sponsoring agency. The original closing date shown in the source information is July 28, 2022, and the award ceiling and expected number of awards are not specified in the provided text.
Eligibility is broad and includes many types of U.S.-based organizations and governments. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses. The FOA also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. This wide eligibility is consistent with the program's goal of expanding HIV research capacity and strengthening research networks in diverse settings.
At the same time, the FOA sets clear limits on non-U.S. applicants. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed. In practical terms, this means a U.S. applicant organization can include certain international collaborations or activities as a foreign component when permitted under NIH policy, but a foreign institution cannot serve as the primary applicant organization for this center grant.
Finally, the "Clinical Trial Not Allowed" designation means applicants must propose center activities and supported research that do not include NIH-defined clinical trials under this award. The D-CFAR is therefore positioned primarily as an infrastructure and capacity-building mechanism to support and coordinate HIV/AIDS research and investigator development, while staying within NIH rules that exclude clinical trial conduct under this particular FOA.Apply for PAR 20 107
- The National Institutes of Health in the education, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.233, 93.242, 93.279, 93.307, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.847, 93.855, 93.865, 93.866, 93.989.
- This funding opportunity was created on 2020-02-03.
- Applicants must submit their applications by 2022-07-28. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): NIH PAR-20-107 Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
What is PAR-20-107?
PAR-20-107 is a National Institutes of Health (NIH) funding opportunity titled "Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)." It supports the creation or strengthening of Developmental Centers for AIDS Research (D-CFARs) to expand and improve HIV/AIDS research capacity through centralized leadership and shared research infrastructure.
What is a D-CFAR?
A D-CFAR (Developmental Center for AIDS Research) is a center-based program designed to build an institutional environment that supports many HIV/AIDS investigators. It emphasizes shared administrative leadership, coordinated services, and shared core facilities that individual labs or stand-alone projects often cannot sustain on their own.
Is this funding for a single research project?
No. This is a P30 center grant mechanism focused on infrastructure and capacity building. Rather than funding one discrete research project, it supports shared resources, expertise, and services that make HIV/AIDS research more efficient, collaborative, and competitive across multiple investigators and projects.
What is the main goal of the D-CFAR program under this FOA?
The main goal is to expand and improve HIV/AIDS research capacity by providing centralized administrative leadership and shared research infrastructure. The program is intended to strengthen institutional research ecosystems and enable investigators to access tools and support that would be difficult to maintain through separate, individual grants.
What kinds of support can a D-CFAR provide?
Based on the description provided, a D-CFAR can provide centralized administrative leadership, shared core facilities, specialized expertise, and coordinated services. These shared resources are intended to reduce duplication of expensive capabilities, streamline access to support services, and improve coordination among investigators.
What research areas does the D-CFAR emphasize?
The program emphasizes interdisciplinary collaboration across the full spectrum of HIV/AIDS research. This includes (as described) basic science, clinical research (within the "clinical trial not allowed" limitation), behavioral and social sciences, epidemiology, implementation science, and other related disciplines contributing to HIV prevention, treatment, cure research, comorbidities, and health equity.
How does the D-CFAR encourage collaboration?
The D-CFAR structure is intended to connect investigators across disciplines by providing shared infrastructure and coordinated services. It aims to reduce unnecessary duplication of resources, standardize methods where helpful, and provide streamlined access to tools and expertise that support multi-investigator collaboration.
What does "developmental" mean in D-CFAR?
"Developmental" refers to the program purpose of helping institutions and research communities mature into a future, full-scale Center for AIDS Research (CFAR). D-CFAR support is positioned as a capacity-building pathway to strengthen the research base, develop collaborations, and improve competitiveness for a standard CFAR award later.
Is the D-CFAR meant to lead to a future CFAR application?
Yes. A central purpose described for the D-CFAR is to position an institution and its investigators to compete successfully for a standard CFAR award in the future by supporting planning, coordination, and shared resources that strengthen the overall HIV/AIDS research environment.
What does "P30" mean in this opportunity?
The FOA uses the P30 center grant mechanism, which is described here as a way to build and sustain shared infrastructure, administrative leadership, and coordinated services that support multiple investigators rather than a single research project.
Are clinical trials allowed under this funding opportunity?
No. The opportunity is designated "Clinical Trial Not Allowed." Applicants must propose center activities and supported research that do not include NIH-defined clinical trials under this award.
Does "Clinical Trial Not Allowed" mean no clinical research is allowed?
Not necessarily. The provided description notes that interdisciplinary work can include clinical research within the limitation that NIH-defined clinical trials are not included under this FOA. The key restriction is that NIH-defined clinical trials cannot be conducted as part of this award.
Who is the sponsoring agency for this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Is this discretionary funding?
Yes. The opportunity is listed as discretionary funding.
What is the funding instrument for PAR-20-107?
The FOA uses the grant funding instrument.
What is the activity category for this opportunity?
It falls within a broad health and social services activity category, consistent with the cross-cutting nature of HIV/AIDS research support.
What CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers, including 93.121, 93.233, 93.242, 93.279, 93.307, 93.361, 93.393-93.396, 93.399, 93.837-93.840, 93.847, 93.855, 93.865-93.866, and 93.989.
Why are there multiple CFDA numbers listed?
The multiple CFDA numbers reflect the multi-institute and cross-cutting nature of NIH HIV/AIDS research support described in the opportunity information.
What types of organizations are eligible to apply?
Eligibility is broad for U.S.-based applicants. Eligible organizations include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The FOA highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly mentions faith-based or community-based organizations among the eligible applicant types.
Are U.S. territories or possessions eligible to apply?
Yes. The FOA lists U.S. territories or possessions among eligible applicant types.
Are federal agencies eligible to apply?
Yes. The FOA indicates eligible federal agencies are included among eligible applicant types.
Are non-U.S. (foreign) organizations eligible to apply as the primary applicant?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as the applicant organization for this opportunity.
Can a U.S. organization include non-U.S. components in its application?
No. The FOA states that non-domestic components of U.S. organizations are not eligible to apply.
Are foreign components allowed at all?
Yes. The FOA indicates that foreign components, as defined in the NIH Grants Policy Statement, are allowed. This suggests that certain international collaborations or activities may be included as a foreign component when permitted under NIH policy, even though foreign institutions cannot be the primary applicant.
What is the closing date for this opportunity?
The original closing date shown in the provided information is July 28, 2022.
What is the award ceiling?
The award ceiling is not specified in the provided information.
How many awards are expected?
The expected number of awards is not specified in the provided information.
What is the overall value of a D-CFAR approach compared to stand-alone grants?
As described, the D-CFAR approach builds shared infrastructure and coordinated services that can reduce duplication of expensive resources, improve access to specialized expertise, standardize methods where helpful, and accelerate progress by making research operations more efficient and collaborative across multiple investigators.
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| HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) Apply for RFA NS 21 010 Funding Number: RFA NS 21 010 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Time-Sensitive Obesity Policy and Program Evaluation (R01 Clinical Trial Not Allowed) Apply for PAR 21 305 Funding Number: PAR 21 305 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed) Apply for RFA NS 22 034 Funding Number: RFA NS 22 034 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Emergency Awards: HEAL Initiative- New Innovator Award (DP2 Clinical Trial Not Allowed) Apply for RFA TR 22 013 Funding Number: RFA TR 22 013 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| HEAL Initiative: Discovery and Functional Evaluation of Human Pain-associated Genes and Cells (U19 Clinical Trial Not Allowed) Apply for RFA NS 22 018 Funding Number: RFA NS 22 018 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,500,000 |
| HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional) Apply for RFA NS 23 003 Funding Number: RFA NS 23 003 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain(R01 Clinical Trial Not Allowed) Apply for RFA NS 22 070 Funding Number: RFA NS 22 070 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $750,000 |
| Catalyst Award for Early-Stage Investigators (ESIs) Pursuing Research on HIV Comorbidities, Coinfections, and Complications (DP1- Clinical Trial Optional) Apply for PAR 23 024 Funding Number: PAR 23 024 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $350,000 |
| Advanced Training in Artificial Intelligence for Precision Nutrition Science Research (AIPrN) Institutional Research Training Programs (T32) Apply for RFA OD 22 027 Funding Number: RFA OD 22 027 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Independent Clinical Trial Not Allowed) Apply for RFA OD 23 003 Funding Number: RFA OD 23 003 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $200,000 |
| Enhancing the Use of the All of Us Research Programs Data (R21 Clinical Trial Not Allowed) Apply for RFA PM 23 001 Funding Number: RFA PM 23 001 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Grants to Enhance the Use of the All of Us Research Programs Data (R03 Clinical Trial Not Allowed) Apply for RFA PM 23 002 Funding Number: RFA PM 23 002 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed) Apply for PAR 23 137 Funding Number: PAR 23 137 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $250,000 |
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| HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional) Apply for RFA NS 23 028 Funding Number: RFA NS 23 028 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,500,000 |
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| HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) Apply for RFA NS 24 019 Funding Number: RFA NS 24 019 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Apply for PAR 24 075 Funding Number: PAR 24 075 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required) Apply for PAR 24 076 Funding Number: PAR 24 076 Agency: National Institutes of Health Category: Education, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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